ea0011p682 | Reproduction | ECE2006
Vignozzi L
, Morelli A
, Filippi S
, Donati S
, Luconi M
, Zhang XH
, Ambrosini S
, Vannelli GB
, Mirone V
, Forti G
, Maggi M
Objectives: Radical prostatectomy is an effective therapy for clinically localized prostate cancer. A significant number of men develops post-prostatectomy erectile dysfunction (PPED), due to surgery-related nervous damage. PPED is relatively refractory to PDE5i therapy. In a rat model of bilateral cavernous neurotomy we evaluated whether chronic tadalafil treatment (CTT) could ameliorate anatomical and functional damage to corpora cavernosa (CC).Methods...